Federer lost in 2006 1–6, 6–1, 6–4, 7–6 and in 2007 6–3, 4–6, 6–3, 6–4 to Nadal; both years in four sets.

Svetlana Kuznetsova (RUS)[4] v. Nadia Petrova (RUS)[25]
Kuznetsova is often overlooked and more attention is given to other more flashy players, but her mix of topspin and slice is very tough to beat.
Winner: Kuznetsova

Maria Sharapova (RUS)[1] v. Karin Knapp (ITA)[32]
World number one and Australian Open champion Sharapova has struggled in both of her prior matches but should sense a rare opportunity to win the French Open without beating any grand slam champions with the Friday loses of the Williams sisters and the retirement of Justine Henin.
Winner:Sharapova

Jurgen Melzer (AUT) v. Gael Monfils (FRA)
Monfils' physical game should serve him well on the red dirt unless he unravels in errors.
Winner:Monfils

Roger Federer (SUI)[1] v. Mario Ancic (CRO)
Ancic is a formidable opponent but Federer should win in four sets.
Winner: Federer

Victoria Azarenka (BLR)[16] v. Francesca Schiavone (ITA)[18]
Schiavone's a tough claycourter and should move forward if she can play her game consistently today.
Winner: Schiavone

Lleyton Hewitt (AUS)[25] v. David Ferrer (ESP)[5]
Hewitt's a major counterpuncher but actually one of the last Wimbledon winners other than Federer.
Winner: Hewitt

Olga Govortsova (BLR) v. Elena Dementieva (RUS)[7]
If Dementieva had a better serve she would be more feared on the tour, but she should have enough game to win today.
Winner: Dementieva

Julien Benneteau (FRA) v. Robin Soderling (SWE)
Two tough players both with outstanding groundstrokes. Soderling's consistency may be a deciding factor.
Winner: Soderling

Dinara Safina (RUS)[13] v. Jie Zheng (CHN)
Safina's cleaned up her game and is on a roll in Paris.
Winner: Safina

Jelena Jankovic (SRB)[3] v. Dominika Cibulkova (SVK)[28]
The human backboard, Jankovic is tough to beat on the dirt in France.
Winner: Jankovic

Robby Ginepri (USA) v. Florent Serra (FRA)
America's last hope Ginepri could win in five sets or four if he plays his best tennis. Otherwise America is left with zero singles players.
Winner: Ginepri

Nikolay Davydenko (RUS)[4] v. Ivan Ljubicic (CRO)[28]
Davydenko loses some matches he should win for whatever reason, but can win many matches on clay due to his superior groundstrokes alone.
Winner: Davydenko

Agnes Szavay (HUN)[12] v. Petra Kvitova (CZE)
Newcomer Szavay attacks the ball with flair and should win today.
Winner: Szavay